Previous

2012

15/11/2012

Robert Plomin, MRC Research Professor and Deputy Director of the Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry.
Title: "Genetic influence in cognitive development: DNA estimates"
Abstract: It is now possible to use DNA to estimate genetic influence in any large sample of unrelated individuals (Genome-wide Complex Trait Analysis, GCTA). Our work using GCTA has confirmed three findings about cognitive development that previously emerged from the classic twin design: (1) Diverse cognitive abilities are all moderately heritable; (2) The same genes affect diverse cognitive and learning abilities; and (3) From childhood to adolescence, the heritability of general cognitive ability (aka intelligence) increases even though genetic effects are stable. These GCTA results suggest that genetic influences on cognitive abilities, and presumably the brain structures and functions that underlie them, can be substantially accounted for by the additive effects of common variants used on current DNA arrays. The results also imply that genetic effects are highly polygenic (many genes affect each trait) and highly pleiotropic (each trait is affected by many genes).

23/11/2012

Philip Ball, science writer and current contributor and previous editor of Nature
Title: "Water in the Cell"
Abstract: Water is a profoundly unusual liquid, and its peculiarities may make it uniquely suited to act as life's matrix. Even if this were not so, however, we should expect the effects of nanometre-scale confinement and inhomogeneities owing to surface effects to alter the liquid's properties in the cell relative to those in the bulk. Whether water's unusually high degree of local structure makes such influences even more marked than for 'normal' liquids remains an open question, with potentially important consequences for biomolecular interactions.

30/11/2012

Gareth Ball , MRC special training fellowship in biomedical informatics
Title: "Structural Connectivity and Networks in Preterm Brain"

07/12/2012

Shaihan Malik, Lecturer Department of Imaging Sciences and Biomedical Engineering
Title: "Introduction to Parallel Transmission in MRI"

14/12/2012
 
David Cox
Title: "Neonatal cardiac atlasing using MRI - Update of work in progress"
 

2013

09/01/2013

Anton Kichev, Postdoctoral Research Associate in Mechanisms of Perinatal Brain Injury
Title: "TRAIL and TWEAK signalling and cell death in the immature CNS after hypoxia-ischaemia and inflammation"

17/01/2013

Ghislaine Dehaene-Lambertz, Senior Researcher, Head of the cognitive development team, INSERM-CEA Cognitive Neuroimaging Unit, Orsay, France
Title:"We investigate high-level human cognitive functions using experimental psychology, neuropsychology and neuroimaging approaches (functional magnetic resonance imaging, fMRI; magneto- and electro-encephalography, MEG & EEG)." 

01/02/2013

Chiara Nosarti, Senior Lecturer in Mental Health Studies and Neuroimaging, Institute of Psychiatry, King's College
Title: "Neural substrates of high-order cognitive processing in adolescents and adults born preterm".

08/02/2013

Kanwal Bhatia, Research Associate in Biomedical Image Analysis, Department of Computing, Imperial College London
Title: "Manifold learning in medical imaging".

22/02/2013

Jean Pierre Lin, Consultant Paediatric Neurologist at Guy's and St Thomas' Hospital, Children's Neuroscience Service, Guy's and St Thomas'
Title: "Deep Brain Stimulation in the treatment of children with dystonia"

01/03/2013

Claire Thornton, Lab Head of the Perinatal Brain Injury Group, Centre for the Developing Brain.
Title: "Investigating the role of p53 in perinatal brain injury"
Abstract: The tumour suppressor gene p53 is a well-known transcriptional activator with targets ranging from cell cycle checkpoint, apoptosis, repair and senescence, all designed to regulate the cell’s response to stress.
Recent studies have shown that expression and mitochondrial localisation of p53 increase after neonatal HI, as do a number of p53-regulated pro-apoptotic targets; we therefore hypothesised that inhibition of p53 translocation and its subsequent downstream interactions may be protective in neonatal hypoxia-ischaemia (HI)-mediated stress.
In a recent study, our collaborators found that inhibition of mitochondrial p53 resulted in long-lasting protection in a mouse model of HI. Injection of PFT-μ (Pifithrin-µ; inhibitor of mitochondrial p53) post-HI in rats and mice resulted in reduced loss of grey and white matter and prevention of behavioural deficits seen in the vehicle-treated animals.
Our subsequent in vitro studies (and the focus of this talk) have generated a more detailed knowledge of the regulation of p53 by pifithrin, and have implicated an unexpected mechanism contributing to this protection.

08/03/2013

Steve Williams, Professor of Imaging Sciences, Director and Head of the Centre for Neuroimaging Sciences, Institute of Psychiatry and Maudsley Hospital, King’s College London.
Title: "Neuroimaging at KCL - Pre CDB"


14/03/2013
Archontis Giannakidis, Physicist Postdoctoral Fellow Researcher, Lawrence Berkeley National Laboratory, Berkeley, California, USA
Title: “Addressing the Challenges of Cardiac Diffusion Tensor MRI ”

15/03/2013

Paul Aljabar, Lecturer in Imaging Sciences
Title: “Sparse regression and Stability selection: Background and some example neuroimaging applications”

22/03/2013

Tomoki Arichi, Clinical Lecturer in Paediatric Neurology
Title: "Functional Magnetic Resonance Imaging of the Neonatal Brain".

26/04/2013

Daniel Lumsden, Clinical Research Fellow, Complex Motor Disorder Service, Evelina Children's Hospital
Title: "Neuroimaging issues in Paediatric Deep Brain Stimulation"

03/05/2013

Karla Miller, University Research Lecturer, Wellcome Trust Career Development Fellow, Oxford Centre for Functional MRI of the Brain (FMRIB), John Radcliffe Hospital, Oxford
Title: "Novel measures of white matter microstructure using diffusion- and susceptibility-weighted MRI"

07/05/2013

Marc Seal, Group Leader, Developmental Imaging, Murdoch Childrens Research Institute; Senior Research Fellow, Department of Paediatrics, The University of Melbourne
Title: "Neurodevelopmental Research in the antipodes - a perspective from Melbourne".

10/05/2013

Michel Thiebaut de Schotten, Research Fellow, Institute of Psychiatry, King's College London
Title: "A fronto-parietal network for spatial Awareness".

Abstract: Looking for a friend in the crowd or avoiding a sudden danger are two actions based on the quality of our visuo-spatial attention. Behavioural tests and brain imaging technology demonstrated that visuo-spatial attention is a specialized function of the right hemisphere of the brain. However, anatomical features supporting this specialization have remained elusive. We scanned volunteers with a novel brain imaging technology that can depict the white matter connections, and we measured the degree of specialization of the right hemisphere for visuo-spatial attention with behavioural tests. Exploring the brain circuits, we found white matter connections whose size predicts the degree of specialization of the right hemisphere for visuo-spatial attention. Whilst a damage of this connection in the right hemisphere can predict chronicity of the visuospatial deficits, the lateralisation of this same connection may be predictive of visuo-spatial recovery.

24/05/2013
Claire Booth, Academic Clinical Lecturer in Paediatric Immunology, Molecular Immunology Unit, Institute of Child Health, UCL
Title: "Gene therapy - from Bench to Bedside...and brain"

31/05/2013
Michiel Klitsie, Visiting Researcher in Technical Medicine
Title: "Auditory neonatal fMRI: a feasibility study"

07/06/2013
Piergeorgio Salvan
Title: "Roadworks on Memory Lane"

07/06/2013
Marcus Kaiser, Reader in Neuroinformatics, School of Computing Science, Newcastle University
Title: "The Human Green Brain Project: Computer Models of Connectome Development"

10/06/2013
Edgardo Szyld MD, Neonatologist and Researcher, Weston Visiting Professor, from Buenos Aires. Argentina, Adjunct professor, preventive medicine, Icahn School of Medicine at Mt. Sinai, New York
Title: "Common difficulties when performing multicentre clinical trials"

11/06/2013, Imaging Sciences Seminar
Alan Groves, Anthony Price and David Cox, King's College London
Title: "Functional Cardiac MRI in the newborn"Alan Groves

14/06/2013, Bobbi Fleiss, Research Associate, King's College London
Title: "Understanding the role of neuroinflammation in injury to the developing brain"

21/06/2013, Nora Tuson, Clinical Research Fellow, King's College London
Title:"Imaging biomarkers of hypoxic-ischaemic encephalopathy"

28/06/2013, Pierre Gressens, Professor of Fetal and Neonatal Neurology, King’s College London
Title: "Tertiary brain injury : a new hope for treating perinatal brain damage ?"


12/06/2013, Manon Benders, Pediatrician - Neonatologist, Wilhemina Children's Hospital, Departmet of Neonatology, Utrecht, Netherlands
Title: 'MRI in the neonate: clinical application or research tool?'
"Our main research line is focussed on: ‘Neonatal Neurology’. This research line is consisting out of early prediction of short- and long-term outcome using neuro-imaging techniques (cranial ultrasound, MRI with volumetrics and DTI) and neurophysiological techniques (amplitude integrated EEG) in relation to long-term follow-up in infants treated in the Neonatal Intensive Care Unit. The other research line is “Neuroprotection”. Quantitative MRI in preterm and term equivalent age up to 3 months of age are being used in the approach of evaluating neuroprotection strategies. "

19/07/2013, Regina Vontell, King's College London
Title: 'Beginners guide to understanding Toll-like receptor 3 expression in neurons in the developing brain'

23/07/2013, Dr Jeroen Dudink
Title: "A neonatologist in the neuroscience department"

30/08/2013, Anne Cameron
Legal Compliance Manager, King's College London
Title: "Information Governance talk"

13/09/2013, Jonathan Noble
Pre-registrant Clinical Scientist and PhD student at the One Small Step Gait Laboratory, Guy's Hospital.
Title: "Muscle properties in cerebral palsy"

1/11/2013

Speakers: Prachi Patkee, Piergiorgio Salvan, Michelle Krishnan
New PhD students, Centre for the Developing Brain

Titles:

Prachi Patkee: tbc

Piergiorgio Salvan: "Early development of hemispheric specialization"

Michelle Krishnan: "Combining imaging and genomics to study brain development in preterm infants"

8/11/2013

Speaker: Donald Tournier
Senior Lecturer, Centre for the Developing Brain

Title: "Apparent fibre density: a framework for voxel-based group analysis of advanced diffusion MRI data"

15/11/2013

Speaker 1: Serge Vasylechko
PhD student, Centre for the Developing Brain
Title: "Motion-tolerant fetal T2* relaxometry"

Speaker 2: Giulio Ferazzi
PhD student, Centre for the Developing Brain
Title: "Resting State fMRI in the moving fetus: a robust framework for motion correction" 

22/11/2013

Speaker: Prof Henrik Hagberg
Centre for the Developing Brain, Perinatal Brain Injury Group.

Title: "Magnesium for neuroprotection in pregnancies at risk of preterm birth?"

29/11/2013

Speaker: Dr Verity McClelland
Clinical Lecturer in Clinical Neurophysiology at King's College Hospital, London.

Title: "Central Motor Conduction Times and Somatosensory Evoked Potentials in Children with Dystonia"

17/01/2014
Speaker: Rui Teixeira
PhD student, Centre for the Developing Brain
Title: "Advance MR Imaging from Adults to Neonates"

20/09/2013

Dr Frank Hirth
Department of Neuroscience, Institute of Psychiatry, King's College London

Title: "Evolutionary conserved mechanisms in brain development and disease"

31/01/2014

Speaker: Helen Stolp

Research Associate, Centre for the Developing Brain
Title: "Clarifying the brain: bridging the gap between MRI and histology"

7/02/2014
Speaker: Brigette Vollmer
Senior Lecturer in Paediatric and Neonatal Neurology, Southampton University Hospitals NHS Trust.
Title: "tbc"

21/2/2014

Speaker: Dr Christina Malamateniou
Lecturer, Centre for the Developing Brain

Title: tbc

28/2/2014
Speaker: Lynne Meehan
Title: Open Access

07/03/2014

Speaker: Dr Silvia Gullino
Kingston University London / Kings College London
Title: "At the crossroads: spatial planning, citizen science and parent-led research"

14/03/2014

Speaker: Dr David Cox

Clinical Research Fellow, Cardiovascular Imaging, Centre for the Developing Brain
Title: "Neonatal Cardiac MRI - Research for the next generation"

21/03/2014

Speaker 1: Michelle Krishnan
PhD Student, Centre for the Developing Brain
Title: "Highlights from the International Genomics Conference"

Speaker 2: Neonatal Society Practice seminars

Cherry Alviani, Centre for the Developing Brain

28/03/2014

Speaker: Dr Laura Andreae
Lecturer, MRC Centre for Developmental Neurobiology, KCL
Title: "Synapse formation: a new role for glutamate"

04/04/2014

Speaker: Andria McGrath
Library Services, King's College London
Title: "Pure Database"

11/04/2014

Speaker: Slava Karolis
Institute of Psychiatry, King's College London
Title: "Alterations of structural connectome in adults born very premature"

25/04/2014

Speaker: Dr Veronique Miron
Centre for Regenerative Medicine, University of Edinburgh
Title: "The regenerative role of macrophages in white matter repair"

02/05/2014

Speakers: Rui Teixeira, Fran Padormo, Giulio Ferrazzi, Arian Begiri, Shiahan Malik

Centre for the Developing Brain

Title: ISMRM Practice seminars

09/05/2014

Speaker: Dr Rick Southworth

Department of Imaging Chemistry and Biology, KCL

Title: "PET imaging of the hypoxic heart, and the role of hexokinase in cardiac protection"

6/05/2014

Speaker 1: Harriet Cullen
PhD Student, Centre for the Developing Brain
Title: "The changing state of rest: time-varying connectivity in resting state fMRI" 

Speaker 2: Cherry Alviani

PhD Student, Centre for the Developing Brain

Title: "The role of Caspase-2 in neuronal cell death in hypoxic-ischemic brain injury"

23/05/2014

Speaker 1: Joshua van Ameron
PhD Student, Centre for the Developing Brain
Title: "Fetal MR: Heart Imaging and Brain Atlasing"

Speaker 2: Paul Aljabar

Department of Biomedical Engineering, KCL

Title: "TBA"

30/05/2014

Speaker: Lucilio Cordero Grande 

Research Associate, Centre for the Developing Brain

Title: "Sensitivity encoding for aligned multi-shot MR reconstruction: application to motion correction in neonatal imaging"

06/06/2014

Speaker 1: Catherine Williamson
Professor, Department of Women's Health, King's College London
Title: "Maternal cholestasis in pregnancy- aetiology and metabolic implications in the mother and fetus"

Speaker 2: Georgia Panacleovoulou 

Research Associate, Department of Surgery & Cancer, Imperial College London

Title: "Altered metabolic tissue activity in pregnancy"

13/06/2014

Speaker: Dr Fran Padormo

Research Associate, Centre for the Developing Brain

Title: "Parallel Transmit MRI"

20/06/2014

Speaker: Dr Freek Hoebeek

Department of Neuroscience, University of Rotterdam

Title: "Cerebellar impact on thalamo-cortical networks in health and disease"

26/06/2014 (1pm)

Speaker: Esben Petersen

Department of Radiology, University Medical Centre Utrecht

Title: "Cerebral Blood Flow and Oxygen Metabolism Imaging in Neonates"

27/06/2014 

Speaker: Kerstin Pannek 

Biomedical Image Analysis Group, Imperial College London

Title: "Diffusion MRI of the preterm infant brain"